2000/2001 US MSPPSA report on DNA Amplification
227 pages, 131 graphs and tables
Published: August 1, 2000
A fresh market research report by PhorTech International provides astounding details concerning the US and North American market for DNA amplification products, including a powerful drive towards acquisition of real-time & quantitative PCR instrumentation. This most thorough and recent analysis of the market from 1995 through 2001 shows that new high-end instruments with real-time/quantitative PCR capabilities now account for half the dollars spent on thermal cyclers today.
Today, 57.2% of bioresearchers in the US, or 69,100 individuals currently use DNA amplification techniques. The detailed report analyses put combined instrument and reagent sales for 2000 in excess of $400 million, and almost evenly split between thermal cyclers and thermostable enzymes and kits.
This comprehensive 227 page study, which forms part of PhorTech's MSPPSA series, examines the installed base of thermal cyclers as well as the annual consumption of thermostable enzymes in the US with additional input from Canadian researchers. Unit and dollar sales per year, market sizes and growth rates, plus unit and dollar supplier shares for both instruments and enzymes were calculated. This analysis is based upon the analysis of 577 responses received from a cross-section of life science researchers earlier this year.
Particular emphasis was made to investigate group sharing of instrumentation,
trends in the sample capacity of thermal cyclers, as well as the
trend in the puchase of real-time/quantitative thermal cyclers.
Both unit and dollar market shares are measured for each of these
segments. In addition, the most frequently mentioned thermal cyclers
are identified by name, along with the mean prices paid per instrument
and the relative frequency with which each instrument was reported
in the audit database.
When looking at thermostable enzymes, we first analyzed the overall
market for thermostable enzymes and subsequently analyzed those
used for cycle sequencing separately from enzymes used for more
traditional amplification applications. While Taq still reigns
as overwhelming leader, many new trademarked enzymes seem to have
established themselves with significant market presence. The market
leader is no surprise, but some tough companies provide this supplier
with significant competition. New in this report, we also examine
the primary suppliers for nucleotides used for amplification and
identify four who outsell Applied Biosystems as well as thirty
odd who sell less. Do you know where your company stands?
When looking at thermostable enzymes, we first analyzed the overall market for thermostable enzymes and subsequently analyzed those used for cycle sequencing separately from enzymes used for more traditional amplification applications. While Taq still reigns as overwhelming leader, many new trademarked enzymes seem to have established themselves with significant market presence. The market leader is no surprise, but some tough companies provide this supplier with significant competition. New in this report, we also examine the primary suppliers for nucleotides used for amplification and identify four who outsell Applied Biosystems as well as thirty odd who sell less. Do you know where your company stands?
Purchase plans for instrumentation as well as thermostable enzymes was examined in detail, with projections made for the coming 12 months along with sorted tables of verbatim replies from respondents regarding the suppliers and models they were considering as well as what suppliers they would refuse to do business with. Reviewing these comments shows which suppliers face a bright future and which face a bleak year ahead.
A comprehensive section on amplification methodologies includes an analysis of throughput, applications, the degree to which various enzymes and procedures are used, and the preferences for kits versus individual reagents versus master mixes. The report includes the verbatim comments from 498 researchers explaining their preference. Quantitative values are obtained for typical reaction volumes, magnesium concentration and type of reaction vessel. Respondents were running from ten to ten thousand thermal cycler reactions monthly, with PCR-based applications (such as RT-PCR) the most frequently mentioned.
In addition, respondents report on their use of various 'hot start' procedures and 336 explain why they select the procedure they use.
The reasons for choosing the most recent thermal cycler purchased as well as satisfaction with that decision, are measured, with high scores for many of the companies supplying to this market. Leading companies are then ranked in six key areas of customer satisfaction, with the second-ranked supplier showing increased ratings for the third straight time that we have made these measurements in this report series. These same analyses are performed for the crowded field of suppliers of thermostable enzymes. While, respondents seem to be more pleased with their enzymes than with their instruments, possibly due to the heightened competition in that market, a few unsuspecting suppliers are doing terribly. Do you know where your company stands in comparison? The readers of this report know exactly where they stand in relation to everyone else.
The suggestions on existing products given by over 360 respondents delve deeper than the typical price concerns into technically sound, and manageable improvements. Respondents are also specifically asked to choose among a list of supplier-derived improvements to point out which would be most important to their work. These covered both enzyme and instrument-related issues and detailed sought after practical, technically-based enhancements.
This report is undoubtedly the most complete analysis of the amplification
market in the US today and has already been purchased by more
than a dozen companies determined to strengthen their position
in this lucrative market. With one of the largest datasets to
date, and enhanced by 131 graphs and tables, this study provides
an in-depth look at the amplification user's current needs and
future expectations. This report should be considered essential
reading for anyone seriously intending to succeed in this increasingly
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