1998/1999 US Special Report on Recombinant Protein Expression Systems

155 pages, 65 graphs and tables

Published: May 27, 1998

Price: $2795

Two Suppliers in Head-to-Head Competition for the Leading Spot in the US Protein Expression Market

By client request, our latest report is in a completely new area: Recombinant Protein Expression Systems. An impressive investigation into this exciting growth market, this new market research report places the current U.S. protein expression kit market at over $30 million, with two suppliers sharing the number one position.

The 155 page Special MSPPSA Report is based upon more than 900 responses to surveys sent out earlier this year. The massive database itemizes approximately $4 million spent by respondents themselves on these products. This rich dataset enables a detailed examination of this market and its important segments. For example, the report contains individual sections for the four most common cell systems - mammalian, baculovirus/insect, yeast and prokaryotic - selecting the leader for each of these categories. This permits the identification of a different company as market leader in the case of the most commonly used system, prokaryotic cells. Not only is the current consumption of these products analyzed, but the expected change in use over the coming 12 months is also measured, demonstrating a healthy growth rate. A groundwork is provided by comparisons with previous US reports in related areas.

An entire section of the report is devoted to an analysis of recombinant protein isolation and purification methodologies, beginning with the types of protein expressed, the purification methods utitlized and purification yield obtained. Also investigated were the requirements for type of activity and post-translational modifications, finishing with an open-ended probe regarding downstream applications. The broad cross-section of researchers yield hundreds of particularly valuable, detailed, and specific comments.

The remainder of the report is divided into 4 sections, one dealing with each of the major cell types used for expression. Respondents were first asked about their use of mammalian cells, and to choose from a broad list of expression systems and/or vectors used. A final question in this section concerned the most frequently used epitope tag.

The next section queried those working with insect and baculovirus expression systems, examining the specific type of baculovirus DNA and baculovirus transfer vectors employed, as well as the use of nonlytic stable systems and particular insect cell lines. Next, a single question for users of yeast cells asked which strain was used. Finally, the section examining prokaryotic cells began with an inquiry into the type of system used, followed by questions about the promoter, fusion tags and protease cleavage enzymes. These highly targeted enquiries create workable profiles of the typical user for any supplier wanting to better target their audience.

The report assesses the attitudes and expectations of a cross-section of researchers in the US, representing over 45,000 individuals using these products. Timely and pertinent insight into customer satisfaction issues is provided through a series of questions which allow researchers to describe any negative experiences or impressions associated with specific suppliers. Companies also receive positive feedback for excellence in 5 key performance areas, including product quality and value. Suggestions for improvements in existing products, in addition to specific requests for new products, provide market opportunities for the astute company looking for sustainable competitive advantage.

Over 65 graphs and tables distill a wealth of data into a clear and salient tool for understanding this previously uncharacterized market. As the first exploration into the Protein Expression market, this report should be considered indispensable for both current suppliers interested in identifying and improving their present market position, as well as marketing professionals wishing to better understand the vast potential for these products.

For the first time in a multi-client report, this special report includes an electronic version of the report published with color graphics plus the complete respondent database for your own queries and investigation.

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