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2007/2008 U.S. MSPPSA report on Proteomics Research, Volume One: Sample Preparation & 2-D Electrophoresis
252 pages, 167 graphs and tables
Published: August 10, 2007
Increasing Vitality in Proteomics Research - But Better Sample Preparation is Key & 2-D Usage is Up
A fresh report by PhorTech International once again cuts through
the hearsay and prognostications that have alternatively hyped and denigrated
the proteomics market sector. Based upon measured, primary market research
techniques and painstaking analysis, this new report shows the actual extent to
which proteomics research is carried out today. There are now 23,500
Volume One in the 2007/2008 Proteomics series focuses our clients' attention on the critical issue of sample preparation and two-dimensional electrophoresis.
As seen in the screen shot of a few of the questions used in the survey, respondents provided a full audit of samples used in their proteomic research, detailing sources and origins, along with their current and forecast sample throughput. But the key to analysis of these complex mixtures is the removal of abundant and irrelevant proteins. Respondents were asked to describe these in detail and to indicate the degree of removal their needed to achieve, as well as describing the methods they used to achieve these goals.
Hundreds of verbatim comments are presented and analyzed, providing our clients with a wealth of direct feedback regarding methods used and technical problems encountered during sample preparation, descriptions of respondents' areas of research, enumeration of protein classes of interest, suppliers used to provide major products, as well as list of the principal analytical platforms used in proteomics research. Our clients tell us these sections are the equivalent of spending months in the field talking with customers.
The report is filled with the technical details respondents provided. For example, in the graph below, we see the detection limits respondents require for individual proteins. A robust database of more than 400 respondents ensures sufficient size to obtain smooth Gaussian distributions and excellent confidence intervals.
The report also examines two-dimensional electrophoresis in detail. In the pie chart at the top of the next page, we see the share of mentions for suppliers for the combined techniques of 2-D gels followed by mass spectrometry. This section of the report covers many details, such as types of dyes used for visualization, an analysis of both broad and narrow pH ranges used, and the gel formats and brands of instrumentation used for the first dimension separation. Complete details of how prevalent 2-D electrophoresis is within the field of proteomics research, the number of researchers employing this technique, and the average sample throughput and extrapolated total sample throughput of these analyses is also included.
This report is undoubtedly the most comprehensive and realistic
assessment of the current market for proteomics research in the
This fact-filled 250+ page analysis chronicles the present state of the market and is based upon a cross-section of 410 completed responses to an in-depth web-based survey carried out in May 2007. Enhanced by over 160 graphs and tables, this analysis is essential reading for those intending to prosper in this business in the coming years.
A detailed list of contents along with the survey objectives and methodology, as well as the complete demographics analysis for the report and a copy of the survey questionnaire can be downloaded using the link at the bottom of this page.