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2006/2007 U.S. MSPPSA report on DNA Amplification Instrumentation Market Analysis

204 pages, 133 graphs and tables

Published: July 28, 2006

Price: $4395


Real Time PCR Market Blossoms: Now Used by More than Half the Researchers Using DNA Amplification

Of the estimated 135,000 life science researchers working in North America, we know that 91,250 individuals are currently using DNA amplification techniques. What is astonishing is that 57,450 of them are now using real-time/quantitative PCR. This is up sharply from 2002 when we measured only 26,500 bioresearchers using this more advanced approach. Real-time instrument system placements have continued to keep pace with this market segment expansion, with sales that now easily exceed $100 annually in North America, as seen in the graph below.



This data has been gathered through the use of a full audit in which we asked more than 250 randomly selected bio­researchers using real-time PCR techniques to itemize the real-time platforms that they have access to. We collected details on a total of 379 real time platforms placed in service over the past 10 years. The survey audit form is shown on the next page. Respondents specified the brands and models, instrument quantities, dates placed into service, sample capacities, prices paid, and the number of users for each system.











Real-time PCR platforms are expensive and are generally shared among a number of bioresearchers. In order to extrapolate accurately our findings to North American market totals, these sharing factors have to be individually recorded for each instrument. The following graph shows the distribution of sharing for these systems.



These are a few of the conclusions of a new 204-page study, part of PhorTech's MSPPSA series. This series has been developed over the past 13 years to systematically measure market size, market share, growth rates, and supplier performance in key areas of bioresearch. This new report continues the analysis of DNA amplification markets with a detailed investigation into real time PCR platforms, traditional thermal cyclers and quantitative techniques.


The report includes sections covering extensive technical aspects of real-time PCR and the methods used in amplification itself. For example, in the following table, we see the percent of real time PCR users and corresponding population estimates for researchers utilizing various approaches to monitoring real time PCR assays.


North American Population Monitoring Real Time/Quantitative PCR Assays, by Methodology


% Users

# NA Researchers

Intercalating dye






Molecular Beacons



















In addition to real time PCR platforms, we also examined the market for traditional thermal cyclers. In the next graph, we show the dollar market shares for the installed base of thermal cyclers still in service in North America. This data was based upon a full audit of 968 thermal cyclers itemized by 384 randomly selected bioresearchers who completed the survey.



By asking respondents to itemize their thermal cyclers, we have produced an invaluable database of installed instru­mentation. From this wealth of data, we are able to present detailed graphs of both market share and growth rates for the past decade.


We also asked respondents to describe many other aspects of their usage of amplification, including the applications and procedures they utilize. On the next page, we see the percent of respondents currently using various amplification applications.


An entire section of the report is devoted to desired improvements in amplification procedures and products. We asked respondents to specifically rate the importance of 6 key features to improve the performance of real time PCR platforms. The question results are shown below.



As useful as closed-ended questions are, we prefer using open-ended questions to probe for additional information. The open-ended Question 22 and its generous space are shown below. From this, we collected over 250 comments from respondents filled with valuable suggestions.






















Reading these comments is equivalent to spending weeks of time in the field with end-users and provides essential insight for suppliers. A final question in this series probed for desired improvements to the entire process of DNA amplification.


Customer satisfaction ratings are measured separately for leading vendors of real time PCR systems and thermal cyclers. For thermal cyclers, we probed carefully in these areas and asked respondents to rate manufacturers in seven key areas (easiest to use, most reliable quality, best technical and application support, greatest innovator, best value for money, most flexible, and most committed to amplification). These ratings are invaluable both for suppliers to measure their own performance as well as to discover areas of weakness for their major competitors that can be used to obtain competitive advantage. In addition, we asked respondents whether they would purchase the same make and model as their latest real time platform and thermal cycler. From this input, we can calculate satisfaction rates for each major brand of instrument and discern problem areas by supplier.


An entire section of the report is dedicated to future purchase plans and we use this data to project future growth rates and lines of products forecast to grow least and most rapidly. Over-confident suppliers will ignore these statistics at their own peril, while market-savvy suppliers will use this data to increase their market share and avoid market dead zones.


This report is undoubtedly the most comprehensive analysis of the current market for DNA amplification instrumentation in North America. It has already been purchased by astute competitors determined to strengthen their position in this lucrative market. Enhanced by over 130 color graphs and tables, this study provides a penetrating analysis and should be considered essential reading for anyone seriously intending to succeed in this competitive area. Companies mentioned in the report are listed below.


Companies Mentioned in This Report

Applied Biosystems


Bio-Rad Laboratories


Brinkmann Instruments


Continental Laboratory Products

Corbett Life Science




Fisher Scientific

Idaho Technology


MJ Research


MWG Biotech


Roche Applied Science







A detailed summary of the report including table of contents and list of tables and graphs, as well as the methodology and project objectives, the survey demographics, and a copy of the survey questionnaire can be from the links at the bottom of this page..


A companion report focusing on DNA amplification reagents and methodology has also been published.


Original press release for this reportSee original press release for this report in Adobe Acrobat format.

Detailed contents, methodology, demographics, and questionnaire for this reportSee detailed contents, methodology, demographics, and questionnaire for this report in Adobe Acrobat format.

To order this report, click here.