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2003/2004 US Recombinant Protein Expression Systems Report
236 pages, 182 graphs and tables
Published: October 7, 2003
Revealing Details in Fresh, In-Depth Analysis of the U.S. Market for Protein Expression Systems
Recombinant Protein Expression Systems. An impressive investigation into this exciting growth market, this new market research report places the current U.S. protein expression kit market at over $100 million, with the leading supplier now outselling its nearest rivals by a whopping 5:1 ratio.
The new 236 page MSPPSA Report is based upon 370 end-user interviews conducted over the Internet during July. The extensive database itemizes approximately $2 million spent by respondents themselves on these products. This rich dataset enables a detailed examination of this market and its important segments. For example, the report contains individual sections for the five most common cell systems - mammalian, baculovirus/insect, yeast, prokaryotic, and cell-free or in-vitro expresssion systems - selecting the leader for each of these categories. Unlike our earlier report in this area, prokaryotic expression systems still account for the largest dollar spend on these products, but mammalian expression systems are closing the gap rapidly. The market leader now dominates in 4 of the five market segments studied, but another company has a dominant role in the fifth area.
Not only is the current consumption of these products analyzed, but the expected change in use over the coming 12 months is also measured, demonstrating an above-average growth rate.
An additional section is devoted to the specialized area of purifying expressed proteins and studying the downstream applications for these expression products. Topics covered include the types of protein expressed, the purification methods utitlized and purification yield obtained, the number of constructs expressed monthly, and the use of automated purification systems. Also investigated were the requirements for type of activity and post-translational modifications, finishing with an open-ended probe regarding downstream applications. The broad cross-section of researchers yield hundreds of particularly valuable, detailed, and specific comments.
The remainder of the report is divided into 4 sections, one dealing with each of the major cell types used for expression. Respondents were first asked about their use of mammalian cells, and to choose from a broad list of expression systems and/or vectors used. A final question in this section concerned the most frequently used epitope tag.
The next section queried those working with insect and baculovirus expression systems, examining the specific type of baculovirus DNA and baculovirus transfer vectors employed, as well as the use of nonlytic stable systems and particular insect cell lines. Next, a single question for users of yeast cells asked which strain was used. Finally, the section examining prokaryotic cells began with an inquiry into the type of system used, followed by questions about the promoter, fusion tags and protease cleavage enzymes. These highly targeted enquiries create workable profiles of the typical user for any supplier wanting to better target their audience.
The report assesses the attitudes and expectations of a cross-section of researchers in the US, representing over 46,000 individuals using these products. Timely and pertinent insight into customer satisfaction issues is provided through a series of questions which allow researchers to describe any negative experiences or impressions associated with specific suppliers. Companies also receive positive feedback for excellence in 5 key performance areas, including product quality and value. Suggestions for improvements in existing products, in addition to specific requests for new products, provide market opportunities for the astute company looking for sustainable competitive advantage.
Over 182 graphs and tables distill a wealth of data into a clear and salient tool for understanding this previously uncharacterized market. This fresh exploration into the Protein Expression market, our second on this topic, should be considered indispensable for both current suppliers interested in identifying and improving their present market position, as well as marketing professionals wishing to better understand the vast potential for these products.