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2003/2004 U.S. MSPPSA report on Molecular Biology Reagent Systems, Volume Two: Nucleic Acid Amplification, Sequencing, cDNA Synthesis & Cloning, Labeling, Detection & Other Kits

236 pages, 278 graphs and tables

Published: September 5, 2003

Price: $3795


Robust Growth Continues for U.S. Molecular Biology Kit Market

PhorTech International's detailed analysis of this market puts total sales substantially above earlier reports. This includes sales of both kits and individual reagents for major segments within this market, including nucleic acid labeling, nucleic acid detection, DNA sequencing, synthesis and amplification from various sources, and reflects broader use among an estimated 85,030 individuals currently using molecular biology reagents in their work. With market segments increasing in complexity and diversity, successful suppliers need to keep close to their customers, with reliable product supply lines, a dedicated commitment to product quality, appropriate pricing, and sensible product improvements.



This 236 page study estimates the present size and growth rate for the US molecular biology kit market as a whole, and for major segments within this market. It details the present market share for major kit categories among leading companies and projects which suppliers have the best prospects for growth in the coming year. As can be seen in the previous graph, market shares continue to evolve with substantial changes noted from our last report published in 2001.


By identifying marketing strengths and weaknesses, and suggesting strategies for development or improvement, the report provides the essential facts needed to sustain competitive advantage. It draws direct comparisons with earlier studies to paint a comprehensive global picture. It includes direct feed-back on the attitudes and expectations of customers and, by profiling researchers most likely to purchase the various kits, it will enable you to target your customers more accurately and efficiently.



From a random cross section of life science researchers from three independent sources, 388 respondents currently using molecular biology reagents in their work completed our anonymous, web-based questionnaire, filling out tabular entries, check-offs, and extensive open-ended probes. Respondents were characterized by their experience using molecular biology techniques, and type of organization. Each was asked to provide detailed audit information itemizing the commercial kits they use, including the brand and type of kit, number of kits used annually, approximate price per kit and their anticipated % change over the next 12 months.


Types of kits included were DNA sequencing (radioactive manual, non-isotopic manual and automated), thermostable enzymes, ribonuclease protection assays, nucleic acid labeling (random primer, nick translation, in vitro transcription, 5' end labeling and direct enzyme labeling of oligos), cDNA synthesis and cloning, and other types (differential display, genotyping/fingerprinting, in vitro transcription (RNA production), in vitro translation, RACE, site-directed mutagenesis and transfection). Separate thermal enzyme purchases were also audited.


In addition to audit questions, respondents were asked to identify their current applications for thermostable enzymes from a list of 17 options including automated cycle sequencing, PCR products cloning, disease diagnosis, allele distinction, fingerprinting, genetic mapping, GMO detection, in vitro labeling, in-situ PCR, LA PCR, manual cycle sequencing, presence of sequencing, quantitative PCR, quantitative RT-PCR, RT-PCR, site-directed mutagenesis and an 'other' option for those performing an unlisted application.



They were also asked which of six cloning applications they currently perform: cDNA cloning, bacterial expression cloning, eukaryotic expression cloning, genomic DNA, PCR product cloning or an 'other' category (write-in), and asked to identify the reverse transcriptase they used (AMV-RT, MMLV-RT, MMLV-RT RNAse H-, Tth or 'other' write-in category). Once again, comparing results with our previous report shows a significant reduction in the use of Tth.


The report itemizes sales of these six categories of molecular biology reagent kits for the leading 36 suppliers to this industry, as well as all other suppliers considered as a group. With this information, product mix charts have been presented for the largest 9 suppliers.



Verbatim input from 347 respondents consider the question of how the stated number of reactions per kit compare with the number the respondent routinely obtains in practice. A further 139 respondents provide suggestions on improvements they would like to see in molecular biology kits. Although the most common theme was lowering the price of kits, other more diverse concerns surfaced, such as adjusting the balance of kit components and improving the kit documentation. More than 160 respondents commented on additional applications for which they would like a commercial kit to become available. Whilst suggestions were extremely diverse, many will provide unique insight to your R&D groups.


We consider this new research study, Molecular Biology Reagent Systems Volume II, essential reading for committed players in this technically demanding but lucrative field. Together with its companion report, Volume I (which includes market analysis for nucleic acid isolation and purification and currently in development), it constitutes the most comprehensive and up-to-date resource available.


Download a free 48 page extract from the report outlining the study objectives and methodology, respondent demographics, table of contents, list of tables and figures, and a copy of the survey questionnaire from the link below.


Original press release for this reportSee original press release for this report in Adobe Acrobat format.

Detailed contents, methodology, demographics, and questionnaire for this reportSee detailed contents, methodology, demographics, and questionnaire for this report in Adobe Acrobat format.

To order this report, click here.